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Mike Lunn Neurologist London


Specialist in Neurology

Neuro-immunology, Neuromuscular disorders, Peripheral nerve disease,

  • Name Dr Mike Lunn
    GMC Number 04040387
    Address National Hospital for Neurology Box 76 Queen Square
    Town/City London
    Post Code WC1N 3BG
    Speciality Neurology
    Sub-Speciality Neuro-immunology, Neuromuscular disorders, Peripheral nerve disease,
    Work Place Tuesday mornings: The Lister Hospital, Chelsea Bridge Road, London SW1W 8RH
    Wednesday afternoon: Private Consulting Rooms of the National Hospital for Neurology, Queen Square, London WC1N 3BG
    Clinic Times
    Monday --:-- To 21:00
    Tuesday 08:00 To 11:30
    Wednesday 16:00 To 19:00
    Thursday --:-- To 21:00
    Friday --:-- To 21:00
    Saturday --:-- To 21:00
    Sunday --:-- To 21:00
  • Qualifications MBBS MA FRCP PhD
    Specialist Interest Peripheral neuropathies
    Neuromuscular disease
    Profile Summary Consultant Neurologist, Clinical Lead in Neuroimmunology and Honorary Senior Lecturer at the National Hospital for Neurology and Nurosurgery. He trained in medicine at Emmanuel College, Cambridge and the Charing Cross and Westminster Hospitals Medical School. He worked at the Royal Brompton and Hammersmith Hospitals before receiving his specialist neurology training in the UK at Guy’s, King’s, St Thomas’ and Charing Cross hospitals, Hurstwood Park Neurosciences Centre and Queen Square, and at the Johns Hopkins Hospital in Baltimore, USA.

    He was appointed to a Consultant position at NHNN in 2005
  • Specialist clinical and research interests are in the inflammatory neuropathies, particularly Guillain-Barré syndrome, CIDP and paraproteinaemic neuropathies.
  • 1: Cregg R, Laguda B, Werdehausen R, Cox JJ, Linley JE, Ramirez JD, Bodi I,
    Markiewicz M, Howell KJ, Chen YC, Agnew K, Houlden H, Lunn MP, Bennett DL, Wood
    JN, Kinali M. Novel Mutations Mapping to the Fourth Sodium Channel Domain of
    Nav1.7 Result in Variable Clinical Manifestations of Primary Erythromelalgia.
    Neuromolecular Med. 2013 Jan 6. [Epub ahead of print] PubMed PMID: 23292638.

    2: Vivekananda U, Lunn MP, Brew S, Miller DH. Cervical transverse myelitis like
    presentation of cranial dural arteriovenous fistula. Clin Neurol Neurosurg. 2012
    Nov 22. doi:pii: S0303-8467(12)00553-7. 10.1016/j.clineuro.2012.10.019. [Epub
    ahead of print] PubMed PMID: 23182605.

    3: Saifee TA, Schwingenschuh P, Reilly MM, Lunn MP, Katschnig P, Kassavetis P,
    Pareés I, Manji H, Bhatia K, Rothwell JC, Edwards MJ. Tremor in inflammatory
    neuropathies. J Neurol Neurosurg Psychiatry. 2012 Sep 5. [Epub ahead of print]
    PubMed PMID: 22952325.

    4: Pitceathly RD, Murphy SM, Cottenie E, Chalasani A, Sweeney MG, Woodward C,
    Mudanohwo EE, Hargreaves I, Heales S, Land J, Holton JL, Houlden H, Blake J,
    Champion M, Flinter F, Robb SA, Page R, Rose M, Palace J, Crowe C, Longman C,
    Lunn MP, Rahman S, Reilly MM, Hanna MG. Genetic dysfunction of MT-ATP6 causes
    axonal Charcot-Marie-Tooth disease. Neurology. 2012 Sep 11;79(11):1145-54. doi:
    10.1212/WNL.0b013e3182698d8d. Epub 2012 Aug 29. PubMed PMID: 22933740; PubMed
    Central PMCID: PMC3525307.

    5: Mattsson N, Zegers I, Andreasson U, Bjerke M, Blankenstein MA, Bowser R,
    Carrillo MC, Gobom J, Heath T, Jenkins R, Jeromin A, Kaplow J, Kidd D, Laterza
    OF, Lockhart A, Lunn MP, Martone RL, Mills K, Pannee J, Ratcliffe M, Shaw LM,
    Simon AJ, Soares H, Teunissen CE, Verbeek MM, Umek RM, Vanderstichele H,
    Zetterberg H, Blennow K, Portelius E. Reference measurement procedures for
    Alzheimer's disease cerebrospinal fluid biomarkers: definitions and approaches
    with focus on amyloid β42. Biomark Med. 2012 Aug;6(4):409-17. doi:
    10.2217/bmm.12.39. Review. PubMed PMID: 22917143.

    6: Zetterberg H, Lunn MP, Herukka SK. Clinical use of cerebrospinal fluid
    biomarkers in Alzheimer's disease. Biomark Med. 2012 Aug;6(4):371-6. doi:
    10.2217/bmm.12.47. PubMed PMID: 22917139.

    7: Goebel A, Lecky B, Smith LJ, Lunn MP. Pain intensity and distribution in
    chronic inflammatory demyelinating polyneuropathy. Muscle Nerve. 2012
    Aug;46(2):294-5. doi: 10.1002/mus.23355. PubMed PMID: 22806382.

    8: Hughes RA, Lunn MP. Neuromuscular disease: IVIg for neuromuscular
    disease-effective but expensive. Nat Rev Neurol. 2012 May 22;8(6):303-5. doi:
    10.1038/nrneurol.2012.92. PubMed PMID: 22614848.

    9: Lunn MP, Nobile-Orazio E. Immunotherapy for IgM anti-myelin-associated
    glycoprotein paraprotein-associated peripheral neuropathies. Cochrane Database
    Syst Rev. 2012 May 16;5:CD002827. doi: 10.1002/14651858.CD002827.pub3. Review.
    PubMed PMID: 22592686.

    10: Murphy SM, Laura M, Fawcett K, Pandraud A, Liu YT, Davidson GL, Rossor AM,
    Polke JM, Castleman V, Manji H, Lunn MP, Bull K, Ramdharry G, Davis M, Blake JC,
    Houlden H, Reilly MM. Charcot-Marie-Tooth disease: frequency of genetic subtypes
    and guidelines for genetic testing. J Neurol Neurosurg Psychiatry. 2012
    Jul;83(7):706-10. doi: 10.1136/jnnp-2012-302451. Epub 2012 May 10. PubMed PMID:

    11: Vanhoutte EK, Faber CG, Merkies IS; PeriNomS Study Group. MRC sum-score in
    the ICU: good reliability does not necessarily reflect "true reliability". Muscle
    Nerve. 2012 May;45(5):767-8; author reply 768-9. doi: 10.1002/mus.23344. PubMed
    PMID: 22499112.

    12: Arthur-Farraj PJ, Murphy SM, Laura M, Lunn MP, Manji H, Blake J, Ramdharry G,
    Fox Z, Reilly MM. Hand weakness in Charcot-Marie-Tooth disease 1X. Neuromuscul
    Disord. 2012 Jul;22(7):622-6. doi: 10.1016/j.nmd.2012.02.008. Epub 2012 Mar 28.
    PubMed PMID: 22464564.

    13: Vanhoutte EK, Faber CG, van Nes SI, Jacobs BC, van Doorn PA, van Koningsveld
    R, Cornblath DR, van der Kooi AJ, Cats EA, van den Berg LH, Notermans NC, van der
    Pol WL, Hermans MC, van der Beek NA, Gorson KC, Eurelings M, Engelsman J, Boot H,
    Meijer RJ, Lauria G, Tennant A, Merkies IS; PeriNomS Study Group. Modifying the
    Medical Research Council grading system through Rasch analyses. Brain. 2012
    May;135(Pt 5):1639-49. doi: 10.1093/brain/awr318. Epub 2011 Dec 20. PubMed PMID:
    22189568; PubMed Central PMCID: PMC3338921.

    14: Hutton EJ, Carty L, Laurá M, Houlden H, Lunn MP, Brandner S, Mirsky R, Jessen
    K, Reilly MM. c-Jun expression in human neuropathies: a pilot study. J Peripher
    Nerv Syst. 2011 Dec;16(4):295-303. doi: 10.1111/j.1529-8027.2011.00360.x. PubMed
    PMID: 22176144.

    15: Trip SA, Saifee T, Honan W, Chandrashekar H, Lunn MP, Yousry T, Koltzenburg
    M, Reilly MM. Chronic immune sensory polyradiculopathy with cranial and
    peripheral nerve involvement. J Neurol. 2012 Jun;259(6):1238-40. doi:
    10.1007/s00415-011-6326-0. Epub 2011 Nov 29. PubMed PMID: 22124665.

    16: Morrow JM, D'Sa S, Page RA, Hilali MA, Lunn MP, Reilly MM. Rituximab
    responsive multiple radiculopathies and cranial nerve palsies in association with
    chronic lymphocytic leukaemia. J Neurol. 2012 Mar;259(3):571-3. doi:
    10.1007/s00415-011-6217-4. Epub 2011 Sep 2. PubMed PMID: 21887515.

    17: Ambrose HE, Granerod J, Clewley JP, Davies NW, Keir G, Cunningham R,
    Zuckerman M, Mutton KJ, Ward KN, Ijaz S, Crowcroft NS, Brown DW; UK Aetiology of
    Encephalitis Study Group. Diagnostic strategy used to establish etiologies of
    encephalitis in a prospective cohort of patients in England. J Clin Microbiol.
    2011 Oct;49(10):3576-83. doi: 10.1128/JCM.00862-11. Epub 2011 Aug 24. PubMed
    PMID: 21865429; PubMed Central PMCID: PMC3187347.

    18: Hamid JS, Meaney C, Crowcroft NS, Granerod J, Beyene J; UK Health Protection
    Agency Aetiology of Encephalitis Study Group. Potential risk factors associated
    with human encephalitis: application of canonical correlation analysis. BMC Med
    Res Methodol. 2011 Aug 22;11:120. doi: 10.1186/1471-2288-11-120. PubMed PMID:
    21859458; PubMed Central PMCID: PMC3189172.

    19: Smith LJ, Murphy SM, Holmes P, Reilly MM, Reiniger L, Thom M, Lunn MP. A
    painful right leg. BMJ. 2011 Mar 16;342:d1009. doi: 10.1136/bmj.d1009. PubMed
    PMID: 21411806.

    20: Singh JA, Wells GA, Christensen R, Tanjong Ghogomu E, Maxwell L, Macdonald
    JK, Filippini G, Skoetz N, Francis D, Lopes LC, Guyatt GH, Schmitt J, La Mantia
    L, Weberschock T, Roos JF, Siebert H, Hershan S, Lunn MP, Tugwell P, Buchbinder
    R. Adverse effects of biologics: a network meta-analysis and Cochrane overview.
    Cochrane Database Syst Rev. 2011 Feb 16;(2):CD008794. doi:
    10.1002/14651858.CD008794.pub2. Review. PubMed PMID: 21328309.

    21: Saifee TA, Reilly MM, Ako E, Rugg-Gunn F, Brandner S, Lunn MP, Leary SM.
    Sarcoidosis presenting as acute inflammatory demyelinating
    polyradiculoneuropathy. Muscle Nerve. 2011 Feb;43(2):296-8. doi:
    10.1002/mus.21890. PubMed PMID: 21254101.

    22: Murphy SM, Khan U, Alifrangis C, Hazell S, Hrouda D, Blake J, Ball J, Gabriel
    C, Markarian P, Rees J, Karim A, Seckl MJ, Lunn MP, Reilly MM. Anti
    Ma2-associated myeloradiculopathy: expanding the phenotype of anti-Ma2 associated
    paraneoplastic syndromes. J Neurol Neurosurg Psychiatry. 2012 Feb;83(2):232-3.
    doi: 10.1136/jnnp.2010.223271. Epub 2011 Jan 4. PubMed PMID: 21205983.

    23: Saifee TA, Elliott KJ, Rabin N, Yong KL, D'Sa S, Brandner S, Lunn MP, Blake
    J, Reilly MM. Bortezomib-induced inflammatory neuropathy. J Peripher Nerv Syst.
    2010 Dec;15(4):366-8. doi: 10.1111/j.1529-8027.2010.00287.x. Erratum in: J
    Peripher Nerv Syst. 2011 Mar;16(1):74. PubMed PMID: 21199108.

    24: Russo M, Laurá M, Polke JM, Davis MB, Blake J, Brandner S, Hughes RA, Houlden
    H, Bennett DL, Lunn MP, Reilly MM. Variable phenotypes are associated with PMP22
    missense mutations. Neuromuscul Disord. 2011 Feb;21(2):106-14. doi:
    10.1016/j.nmd.2010.11.011. Epub 2010 Dec 30. PubMed PMID: 21194947.

    25: Hamid JS, Meaney C, Crowcroft NS, Granerod J, Beyene J; UK Etiology of
    Encephalitis Study Group. Cluster analysis for identifying sub-groups and
    selecting potential discriminatory variables in human encephalitis. BMC Infect
    Dis. 2010 Dec 31;10:364. doi: 10.1186/1471-2334-10-364. PubMed PMID: 21192831;
    PubMed Central PMCID: PMC3022837.

    26: El-Tawil S, Al Musa T, Valli H, Lunn MP, El-Tawil T, Weber M. Quinine for
    muscle cramps. Cochrane Database Syst Rev. 2010 Dec 8;(12):CD005044. doi:
    10.1002/14651858.CD005044.pub2. Review. PubMed PMID: 21154358.

    27: Joint Task Force of the EFNS and the PNS. European Federation of Neurological
    Societies/Peripheral Nerve Society Guideline on management of paraproteinemic
    demyelinating neuropathies. Report of a Joint Task Force of the European
    Federation of Neurological Societies and the Peripheral Nerve Society--first
    revision. J Peripher Nerv Syst. 2010 Sep;15(3):185-95. doi:
    10.1111/j.1529-8027.2010.00278.x. PubMed PMID: 21040140.

    28: Granerod J, Ambrose HE, Davies NW, Clewley JP, Walsh AL, Morgan D, Cunningham
    R, Zuckerman M, Mutton KJ, Solomon T, Ward KN, Lunn MP, Irani SR, Vincent A,
    Brown DW, Crowcroft NS; UK Health Protection Agency (HPA) Aetiology of
    Encephalitis Study Group. Causes of encephalitis and differences in their
    clinical presentations in England: a multicentre, population-based prospective
    study. Lancet Infect Dis. 2010 Dec;10(12):835-44. doi:
    10.1016/S1473-3099(10)70222-X. Epub 2010 Oct 15. Erratum in: Lancet Infect Dis.
    2011 Feb;11(2):79. PubMed PMID: 20952256.

    29: Khaleeli Z, Healy DG, Briddon A, Lunn MP, Reilly MM, Land J, Giovannoni G.
    [Copper deficiency as a treatable cause of poor balance]. Praxis (Bern 1994).
    2010 Sep 22;99(19):1153-6. doi: 10.1024/1661-8157/a000258. German. PubMed PMID:

    30: Sadnicka A, Reilly MM, Mummery C, Brandner S, Hirsch N, Lunn MP. Rituximab in
    the treatment of three coexistent neurological autoimmune diseases: chronic
    inflammatory demyelinating polyradiculoneuropathy, Morvan syndrome and myasthenia
    gravis. J Neurol Neurosurg Psychiatry. 2011 Feb;82(2):230-2. doi:
    10.1136/jnnp.2009.174888. Epub 2010 May 12. PubMed PMID: 20462915.

    31: Hutton EJ, Lunn MP. Treatment in inflammatory neuropathies. Expert Rev Clin
    Immunol. 2010 Mar;6(2):231-45. PubMed PMID: 20402386.

    32: Granerod J, Cunningham R, Zuckerman M, Mutton K, Davies NW, Walsh AL, Ward
    KN, Hilton DA, Ambrose HE, Clewley JP, Morgan D, Lunn MP, Solomon T, Brown DW,
    Crowcroft NS. Causality in acute encephalitis: defining aetiologies. Epidemiol
    Infect. 2010 Jun;138(6):783-800. doi: 10.1017/S0950268810000725. Epub 2010 Apr
    14. Review. PubMed PMID: 20388231.

    33: Khaleeli Z, Healy DG, Briddon A, Lunn MP, Reilly MM, Land J, Giovannoni G.
    Copper deficiency as a treatable cause of poor balance. BMJ. 2010 Apr
    12;340:c508. doi: 10.1136/bmj.c508. PubMed PMID: 20385722.

    34: van Nes SI, Vanhoutte EK, Faber CG, Garssen M, van Doorn PA, Merkies IS;
    PeriNomS Study Group. Improving fatigue assessment in immune-mediated
    neuropathies: the modified Rasch-built fatigue severity scale. J Peripher Nerv
    Syst. 2009 Dec;14(4):268-78. doi: 10.1111/j.1529-8027.2009.00238.x. PubMed PMID:

    35: Lunn MP, Hughes RA, Wiffen PJ. Duloxetine for treating painful neuropathy or
    chronic pain. Cochrane Database Syst Rev. 2009 Oct 7;(4):CD007115. doi:
    10.1002/14651858.CD007115.pub2. Review. PubMed PMID: 19821395.

    36: Lunn MP, Willison HJ. Diagnosis and treatment in inflammatory neuropathies.
    Postgrad Med J. 2009 Aug;85(1006):437-46. doi: 10.1136/jnnp.2008.158303. PubMed
    PMID: 19633010.

    37: Michell AW, Laura M, Blake J, Lunn MP, Cox A, Gibbons VS, Davis MB, Wood NW,
    Manji H, Houlden H, Murray NM, Reilly MM. GJB1 gene mutations in suspected
    inflammatory demyelinating neuropathies not responding to treatment. J Neurol
    Neurosurg Psychiatry. 2009 Jun;80(6):699-700. doi: 10.1136/jnnp.2008.150557.
    PubMed PMID: 19448103.

    38: Lunn MP, Willison HJ. Diagnosis and treatment in inflammatory neuropathies. J
    Neurol Neurosurg Psychiatry. 2009 Mar;80(3):249-58. doi:
    10.1136/jnnp.2008.158303. Review. Erratum in: J Neurol Neurosurg Psychiatry. 2009
    May;80(5):584. Dosage error in article text. PubMed PMID: 19228670.

    39: Lunn MP, Clarke C, Aldeen T. Acute paraplegia in a patient with AIDS and a
    normal CSF examination. J Hosp Med. 2008 May;3(3):279-80. doi: 10.1002/jhm.303.
    PubMed PMID: 18571806.

    40: Lunn MP, Léger JM, Merkies IS, Van den Bergh P, van Schaik IN; Inflammatory
    Neuropathy Consortium; ENMC. 151st ENMC international workshop: Inflammatory
    Neuropathy Consortium 13th-15th April 2007, Schiphol, The Netherlands.
    Neuromuscul Disord. 2008 Jan;18(1):85-9. Epub 2007 Sep 14. PubMed PMID: 17869518.

    41: Lunn MP. Pinpointing peripheral neuropathies. Practitioner. 2007
    May;251(1694):67-8, 71-4, 76-7 passim. Review. PubMed PMID: 17564137.

    42: Allen D, Lunn MP, Niermeijer J, Nobile-Orazio E. Treatment for IgG and IgA
    paraproteinaemic neuropathy. Cochrane Database Syst Rev. 2007 Jan
    24;(1):CD005376. Review. PubMed PMID: 17253554.

    43: Descamps MJ, Barrett L, Groves M, Yung L, Birch R, Murray NM, Linch DC, Lunn
    MP, Reilly MM. Primary sciatic nerve lymphoma: a case report and review of the
    literature. J Neurol Neurosurg Psychiatry. 2006 Sep;77(9):1087-9. Review. PubMed
    PMID: 16914759; PubMed Central PMCID: PMC2077757.

    44: Lunn MP, Nobile-Orazio E. Immunotherapy for IgM anti-myelin-associated
    glycoprotein paraprotein-associated peripheral neuropathies. Cochrane Database
    Syst Rev. 2006 Apr 19;(2):CD002827. Review. Update in: Cochrane Database Syst
    Rev. 2012;5:CD002827. PubMed PMID: 16625561.

    45: Lunn MP, Nobile-Orazio E. Immunotherapy for IgM anti-Myelin-Associated
    Glycoprotein paraprotein-associated peripheral neuropathies. Cochrane Database
    Syst Rev. 2003;(1):CD002827. Review. Update in: Cochrane Database Syst Rev.
    2006;(2):CD002827. PubMed PMID: 12535440.

    46: Gong Y, Tagawa Y, Lunn MP, Laroy W, Heffer-Lauc M, Li CY, Griffin JW, Schnaar
    RL, Sheikh KA. Localization of major gangliosides in the PNS: implications for
    immune neuropathies. Brain. 2002 Nov;125(Pt 11):2491-506. PubMed PMID: 12390975.

    47: Hadden RD, Bensa S, Lunn MP, Hughes RA. Immunoadsorption inferior to plasma
    exchange in a patient with chronic inflammatory demyelinating
    polyradiculoneuropathy. J Neurol Neurosurg Psychiatry. 2002 May;72(5):644-6.
    PubMed PMID: 11971054; PubMed Central PMCID: PMC1737854.

    48: Lunn MP, Crawford TO, Hughes RA, Griffin JW, Sheikh KA.
    Anti-myelin-associated glycoprotein antibodies alter neurofilament spacing.
    Brain. 2002 Apr;125(Pt 4):904-11. PubMed PMID: 11912122.

    49: Lunn MP, Johnson LA, Fromholt SE, Itonori S, Huang J, Vyas AA, Hildreth JE,
    Griffin JW, Schnaar RL, Sheikh KA. High-affinity anti-ganglioside IgG antibodies
    raised in complex ganglioside knockout mice: reexamination of GD1a
    immunolocalization. J Neurochem. 2000 Jul;75(1):404-12. PubMed PMID: 10854286.

    50: Lunn MP, Muir P, Brown LJ, MacMahon EM, Gregson NA, Hughes RA.
    Cytomegalovirus is not associated with IgM anti-myelin-associated
    glycoprotein/sulphate-3-glucuronyl paragloboside antibody-associated neuropathy.
    Ann Neurol. 1999 Aug;46(2):267-70. PubMed PMID: 10443896.
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